![[論文新知] 健康始於腸：“健康”的百歲人端和健康的30歲壯年人有著極度相似的的腸道菌相](https://static.wixstatic.com/media/72dee4_14147af85939420484e722537479788a~mv2_d_1920_1293_s_2.jpeg/v1/fill/w_102,h_69,fp_0.50_0.50,q_90/72dee4_14147af85939420484e722537479788a~mv2_d_1920_1293_s_2.jpeg)
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澳洲昆士蘭大學的研究出一種新式基因療法，有機會能夠讓過敏和哮喘的患者 「一勞永逸，永絕後患」。 [論文來源] Allergen-encoding bone marrow transfer inactivates allergic T cell responses, alleviating airway inflammation. 發表於 JCI INSIGHT《臨床調查雜誌》>> 2 JUN 2017 DOI:10.1053/j.gastro.2017.05.003 澳大利亞昆士蘭大學的一項免疫學研究開發出一種新基因療法，能夠讓嚴重過敏和氣喘哮喘患者“一勞永逸”。該研究已發表在“JCI Insight”上。 由昆士蘭大學Diamantina研究所助理教授Ray Steptoe領導的一個研究團隊發現能夠“關閉”過敏反應的免疫反應。 Steptoe博士說：「過敏或氣喘的發作，是因為免疫細胞對過敏原中的蛋白質起反應。治療哮喘和過敏的挑戰就在於讓這些免疫細胞，即我們俗稱T細胞會形成一種免疫"記憶“，進而能夠對治療產生抵抗作用。 我們現在使用基因療法來消除動物體內的Ť細胞的“記憶”，降低免疫系統的敏感程度，進而使免疫系統能夠接受這些蛋白質。利用一種用於實驗室可導致氣喘的過敏原，這研究成果也可應用於對花生，蜂毒，貝類等及其他物質嚴重過敏症的治療。」 Steptoe博士還補充，這項研究結果將會再進一步做臨床前試驗。「我們接下來要在實驗室中使用人體細胞重現這些結果，我們將造血幹細胞，放入己調整過敏原蛋白質的基因，再把這些細胞注入受體。這個基因工程後的幹細胞將生成新的血細胞，其生成的蛋白質會針